一、 基本情况

姜新义，教授、药剂学博士生导师，2017年入选“山东大学齐鲁青年学者”。近五年，先后主持完成中国和美国斯坦福大学医学院多项科研基金，已在PNAS，Biomaterials，Theranostics等综合性期刊或药剂学专业期刊上已发表SCI论文二十余篇，获得授权发明专利2项。多次应邀在Society for Biomaterials (SFB)，Biomedical Engineering Society (BMES)，Orthopedic Research Society (ORS) Annual Meeting等国际会议上做大会报告。

通讯地址：山东省济南市文化西路44号，山东大学药学院药剂教研室

TEL/ FAX: 0531-88382015

Email: xinyijiang@sdu.edu.cn 

二、 研究领域

1. 基于纳米医学的肿瘤诊断与治疗；

2. 智能药物递释系统与组织工程研究 

三、 工作及学习经历

2017.11 -至今，山东大学 药学院，教授、博士生导师；

2013.4 -2017.10，美国斯坦福大学 医学院，博士后研究员；

2009.9 -2012.6，复旦大学，药剂学 博士；

2006.9 -2009.7，中国药科大学，中药制剂学 硕士；

2002.9 -2006.7，山东中医药大学，制药工程 学士 

四、 社会兼职

中国药学会-药剂学青年委员会委员

中国颗粒学会第三届青年理事会理事

中国颗粒学会-生物颗粒专业委员会委员

美国Society for Biomaterials 会员

美国Biomedical Engineering Society 会员

美国Orthopedic Research Society会员

担任Mathews Journal of Orthopedics，Integrated Medical and Clinical Case Reports，Heighpubs Clinical and Experimental Orthopaedics，British Journal of Orthopedics and Sports Medicine等期刊编委 

五、 教学工作

承担课程：药剂学，生物药剂学与药物代谢动力学，药用高分子材料等 

六、 承担课题

1. 山东大学齐鲁青年学者启动基金；

2. 中国国家自然科学基金青年项目；

3. Stanford Child Health Research Institute (CHRI) Grant；

4. Stanford School of Medicine Dean’s postdoctoral fellowships 

七、 代表性文章

1. Xinyi Jiang, Sergio Fitch, Christine Wang, Christy Wilson, Jianfeng Li, Gerald Grant and Fan Yang. Nanoparticle engineered TRAIL-overexpressing adipose-derived stem cells target and eradicate glioblastoma via intracranial delivery. PNAS, 2016 113 (48) 13857-13862

2. Xinyi Jiang, Christine Wang, Sergio Fitch, Fan Yang*, Targeting Tumor Hypoxia Using Nanoparticle-engineered CXCR4-overexpressing Adipose-derived Stem Cells, Theranostics, 2018, 8(5):1350-1360. 

3. Xinyi Jiang, Hongliang Xin, Jijin Gu, Ximing Xu, Weiyi Xia, Shuo Chen, Yike Xie, Liangcen Chen, Yanzuo Chen, Xianyi Sha, Xiaoling Fang. Solid tumor penetration by integrin-mediated pegylated poly(trimethylene carbonate) nanoparticles loaded with pactlitaxel. Biomaterials, 2013, 34: 1739-1746.

4. Xinyi Jiang, Xianyi Sha, Hongliang Xin, Ximing Xu, Jijin Gu, Weiyi Xia, Shuo Chen, Yike Xie, Liangcen Chen, Yanzuo Chen, Xiaoling Fang. Integrin-facilitated transcytosis for enhanced penetration of advanced gliomas by poly(trimethylene carbonate)-based nanoparticles encapsulating paclitaxel. Biomaterials, 2013, 23(4): 2969-2979.

5. Xinyi Jiang, Xianyi Sha, Hongliang Xin, Liangcen Chen, Xihui Gao, Xiao Wang, Kitki Law, Jijin Gu, Yanzuo Chen, Ye Jiang, Xiaoqing Ren, Qiuyue Ren, Xiaoling Fang. Self-aggregated pegylated poly (trimethylene carbonate) nanoparticles decorated with c(RGDyK) peptide for targeted paclitaxel delivery to integrin-rich tumors. Biomaterials, 2011, 32: 9457-9469.

6. Xinyi Jiang; Hongliang xin; Qiuyue Ren; Jijin Gu; Lingjun Zhu; Fengyi Du; Chunlai Feng; Yike Xie; Xianyi Sha; Xiaoling Fang, Nanoparticles of 2-deoxy-D-glucose functionalized poly(ethylene glycol)-co-poly(trimethylene carbonate) for dual-targeted drug delivery in glioma treatment. Biomaterials, 2014,35(1): 518-29.

7. Xinyi Jiang, Hongliang Xin, Xianyi Sha, Jijin Gu, Ye Jiang, Law Kitki, Yanzuo Chen, Liangcen Chen, Xiao Wang, Xiaoling Fang. PEGylated poly (trimethylene carbonate) nanoparticles loaded with paclitaxel for the treatment of advanced glioma: in vitro and in vivo evaluation. International Journal of Pharmaceutics, 2011, 420(2): 385-394.

8. Xinyi Jiang, Hongliang xin,Jijin Gu, Fengyi Du, Chunlai Feng, Yike Xie, Xiaoling Fang, Enhanced anti-tumor efficacy by D-glucosamine functionalized and paclitaxel loaded poly(ethylene glycol)-co-poly(trimethylene carbonate) polymer nanoparticles. Journal of Pharmaceutical Sciences, 2014, 103(5): 1487-1496. (IF: 2.59)

9. Xinyi Jiang, Taishi Sato, Zhenyu Yao, Michael Keeney, Jukka Pajarinen, Tzu-hua Lin, Florence Loi, Kensuke Egashira, Stuart Goodman, Fan Yang,  Local delivery of mutant CCL2 protein reduced orthopaedic implant wear particle-induced osteolysis and inflammation in vivo. Journal of Orthopeadic Research, 2015, 2016，34(1): 58-64.

10. Michael Keeney, Xinyi Jiang, Maya Yamane, Meelim Lee, Stuart Goodman, Fan Yang. Nanocoating for biomolecule delivery using layer-by- layer self-assembly. J. Mater. Chem. B, 2015, 3(45):8757-8770.

八、 获得专利                                                                                     

授权专利1：一种包载紫杉醇的生物可降解纳米复合物及其制备方法。发明人：方晓玲，姜新义，沙先谊；专利号：201110174751.1;

授权专利2：一种靶向整合素受体的紫杉醇纳米复合物及其制备方法和应用。发明人：方晓玲，姜新义，沙先谊；专利号：201110174752.6. 

九、 成果

2014  Stanford Child Health Research Institute (CHRI) Grant & Postdoctoral Award;

2013  Stanford Dean’s Postdoctoral Fellowships