一、基本情况介绍
唐明潭，1990年9月生，山东大学药学院助理研究员。博士毕业于新西兰奥克兰大学，主要从事靶向纳米药物逆转肿瘤耐药的研究。曾主持新西兰药学教育研究基金会课题。近五年发表SCI论文十篇，其中以第一或通讯作者发表IF>5的论文三篇。
联系方式：mtang@email.sdu.edu.cn
二、学习和工作经历
2021.9-至今山东大学药学院，药剂学，助理研究员
2019.06-2021.05新西兰奥克兰大学，药剂学，博士后（导师：Prof. Zimei Wu）
2015.05-2020.04新西兰奥克兰大学，药剂学，博士（导师：Prof. Zimei Wu）
2009.09-2013.06山东大学药学院，药学，学士
三、研究领域
建立耐药肿瘤动物模型与敏感肿瘤模型对比评价纳米药物递送系统逆转胰腺癌耐药的能力。揭示衰老逃逸在胰腺癌耐药、转移和复发中的作用及应用复合脂质体逆转衰老逃逸。通过脂质体与外泌体的融合提高载药系统的靶向性和药物递送效率
四、教学工作
本科生：《药剂学》。
研究生：《现代药物制剂技术》。
荣获2023年度山东大学药学院青年教师讲课比赛一等奖。
荣获2022年度山东大学药学院青年教师讲课比赛二等奖。
五、社会兼职
中国抗癌协会纳米肿瘤学专业委员会会员
六、发表论文
Nie X., Shi C., Chen X., Yu C., Jiang Z., Xu G., Lin Y.,Tang M., Luan Y. A single-shot prophylactic tumor vaccine enabled by an injectable biomembrane hydrogel (2023)Acta Biomaterialia.
Reginald-Opara, J.N.,Tang, M., Svirskis, D., Chamley, L., Wu, Z. The role of glutathione conjugation on the transcellular transport process of PEGylated liposomes across the blood brain barrier (2022)International Journal of Pharmaceutics, 626, 122152.
Geng, T.,Tang, M., Yee Paek, S., Leung, E., Chamley, L.W., Wu, Z. A simple approach to re-engineering small extracellular vesicles to circumvent endosome entrapment (2022)International Journal of Pharmaceutics, 626, 122153 .
Yang, M.M., Yarragudi, S.B., Jamieson, S.M.F.,Tang, M., Wilson, W.R., Wu, Z. Calcium Enabled Remote Loading of a Weak Acid Into pH-sensitive Liposomes and Augmented Cytosolic Delivery to Cancer Cells via the Proton Sponge Effect (2022)Pharmaceutical Research, 39 (6), pp. 1181-1195.
Reginald-Opara, J.N., Svirskis, D., Paek, S.Y.,Tang, M., O'Carroll, S.J., Dean, J.M., Chamley, L.W., Wu, Z. The involvement of extracellular vesicles in the transcytosis of nanoliposomes through brain endothelial cells, and the impact of liposomal pH-sensitivity (2022)Materials Today Bio, 13, 100212.
Tang, M., Lozano Hernandez, L., Reginald-Opara, J.N., Svirskis, D., Leung, E., Wang, H., Wu, Z. Zebularine suppressed gemcitabine-induced senescence and improved the cellular and plasma pharmacokinetics of gemcitabine, augmented by liposomal co-delivery (2021)International Journal of Pharmaceutics, 602, 120659.
Hart, K., Harvey, M.,Tang, M., Wu, Z., Cave, G. Liposomes to augment dialysis in preclinical models: A structured review (2021)Pharmaceutics, 13 (3), 395.
Yang, K.,Tang, M., Chang, H.-H., Kanamala, M., Davidson, A.J., Wu, Z. Mannosylation of pH-sensitive liposomes promoted cytoplasmic delivery of protein to macrophages: green fluorescent protein (GFP) performed as an endosomal escape tracer (2021)Pharmaceutical Development and Technology, 26 (9), pp. 1000-1009.
Gao, Y.,Tang, M., Leung, E., Svirskis, D., Shelling, A., Wu, Z. Dual or multiple drug loaded nanoparticles to target breast cancer stem cells (2020)RSC Advances, 10 (32), pp. 19089-19105.
Tang, M., Svirskis, D., Leung, E., Kanamala, M., Wang, H., Wu, Z. Can intracellular drug delivery using hyaluronic acid functionalised pH-sensitive liposomes overcome gemcitabine resistance in pancreatic cancer? (2019)Journal of Controlled Release, 305, pp. 89-100.
