
一、基本情况
蔡容,博士,山东大学药学院教授,药物分析专业博士生导师。2018年获得山东大学“齐鲁青年学者”称号。
通讯地址:山东省济南市文化路44号,山东大学药学院
E-mail: rongcai@sdu.edu.cn
二、研究领域
1.基于小分子活性探针的蛋白质组学研究;
2.探索发现新的药物靶点。
三、工作及学习经历
2019.01 - 至今, 山东大学药学院, 教授、博士生导师
2016.07-2019.01,美国加州大学河滨分校,博士后研究员
2010.08-2016.05,美国西弗吉尼亚大学,博士
2006.09-2010.06,中国科学技术大学,学士
四、承担课题
国家自然科学基金青年项目、省级自然科学基金青年项目
五、 代表性学术论文 (限10篇)
(1) Tan, J.; Gao, C.; Ni, L.; Li, M.; Cai, R.* “Chemoproteomic Profiling of Isoprenoid Pyrophosphate Interacting Proteins with Photoaffinity Probes”, Anal. Chem. 2025, 97, 13266-13273.
(2) Gao, C. #; Li, M. #; Tan, J.; Wang, Z.; Xu, J.; Li, W.; Shi, F.; Chen, Z.; Cai, R.* “Acid-Cleavable Guanosine Triphosphate-Photoaffinity Probe for Global Profiling of Guanosine Triphosphate-Binding Proteins and Their Active Sites”, Anal. Chem. 2025, 97, 3293-3301.
(3) Wang, Z.#; Tan, J.#; Li, M.; Gao, C.; Li, W.; Xu, J.; Guo, C.; Chen, Z.; Cai, R.* "Clickable Photoreactive ATP-Affinity Probe for Global Profiling of ATP-Binding Proteins", Anal. Chem. 2023, 95, 17533-17540.
(4) Cai, R.#; Bade, D.#; Liu, X.; Huang, M.; Qi, T. F.; Wang, Y.* "Targeted Quantitative Profiling of GTP-Binding Proteins Associated with Metastasis of Melanoma Cells", J. Proteome Res. 2021, 20, 5189-5195.
(5) Cai, R.; Dong, X.; Yu, K.; He, X.; Liu, X.; Wang, Y.* "Chemical Proteomic Profiling of the Interacting Proteins of Isoprenoid Pyrophosphates", Anal. Chem. 2020, 92, 8031-8036.
(6) Cai, R.; Huang, M.; Wang, Y.* "Targeted Quantitative Profiling of GTP-Binding Proteins in Cancer Cells Using Isotope-Coded GTP Probes", Anal. Chem. 2018, 90, 14339-14346.
(7) Cai, R.#; Ye, X.#; Sun, Q.#; He, Q.; He, Y.; Ma, S.*; Shi, X.* “Anchoring Triazole-Gold(I) Complex into Porous Organic Polymer to Boost the Stability and Reactivity of Gold(I) Catalyst ” ACS Catal. 2017, 7, 1087-1092. (#contributed equally)
(8) Peng, H.; Cai, R.; Chang, X.; Chen, H.*; Shi, X.* “Nucleophile promoted gold redox catalysis with diazonium salts: C–Br, C–S and C–P bond formation through catalytic Sandmeyer coupling”. Chem. Sci. 2016, 7, 6190-6196.
(9) Cai, R.; Lu, M.; Aguilera, E. Y.; Xi, Y.; Akhmedov, N. G.; Petersen, J. L.; Chen, H.*; Shi, X.* "Ligand-Assisted Gold-Catalyzed Cross-Coupling with Aryldiazonium Salts: A Case of External Oxidant Free Redox Gold Catalysis" Angew. Chem. Int. Ed. 2015, 54, 8772-8776.
(10) Cai, R.; Yan, W.; Bologna, M. G.; De Silva, K.; Finklea, H. O.; Petersen, J. L.; Shi, X.* “Synthesis and Characterization of N-2-Aryl-1,2,3-Triazole Based Iridium Complexes as Photocatalysts with Tuneable Photoredox Potential " Org. Chem. Front. 2015, 2, 141-144.